Genetically elevated gamma-glutamyltransferase and Alzheimer's disease
نویسندگان
چکیده
منابع مشابه
Genetically elevated gamma-glutamyltransferase and Alzheimer's disease
Observational epidemiological evidence supports a linear and independent association between serum gamma-glutamyltransferase (GGT) concentrations and the risk of Alzheimer's disease (AD). However, the causality of this association has not been previously investigated. We sought to assess the causal nature of this association using a Mendelian randomization (MR) approach. Using inverse-variance ...
متن کاملMarkedly elevated gamma-glutamyltransferase.
Gamma-glutamyltransferase (GGT) is a highly sensitive but poorly specific liver enzyme commonly used to detect hepatobiliary disease and possible alcohol abuse. Isolated elevations of this enzyme may be due to biochemical anomalies rather than the presence of pathology.
متن کاملelevated serum gamma-glutamyltransferase (ggt) activity and the development of chronic kidney disease (ckd) in cigarette smokers
background elevated serum gamma-glutamyltransferase (ggt) is predictive of various cardiovascular (cv) risk factors including chronic kidney disease (ckd). elevated serum ggt has been recognized in smokers who are likely to develop ckd, but no study has focused on serum ggt and ckd in smokers. objectives the aim of this study was to clarify the associations between cigarette consumption, elevat...
متن کاملAssociation of serum gamma-glutamyltransferase and premature coronary artery disease
BACKGROUND Serum gamma-glutamyltransferase (GGT) has been introduced as a predictive factor for cardiovascular disease. In this study, we investigated the association of serum GGT and premature coronary artery disease (CAD) in candidates for coronary angiography. METHODS In this cross-sectional study, we enrolled male subjects aged ≤45 years and female subjects ≤55 years who were candidates f...
متن کاملAdditive prognostic value of gamma-glutamyltransferase in coronary artery disease.
BACKGROUND Serum gamma-glutamyltransferase activity (GGT) has been documented as an independent cardiovascular risk factor. However, to-date its value has not been compared with C-reactive protein (CRP) and other indexes in a multimarker prognostic strategy in patients with coronary artery disease. METHODS We prospectively evaluated 474 subjects with angiographically documented CAD. GGT and t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Experimental Gerontology
سال: 2018
ISSN: 0531-5565
DOI: 10.1016/j.exger.2018.03.001